基因名称:HSP90AB1 (heat shock protein 90 alpha family class B member 1)
别名: HSP84,HSPC2,HSPCB,D6S182,HSP90B
基因ID:3326
Chromosome(GRCh37) :6 Start: 44213903 End: 44221625 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码热休克蛋白90家族的一个成员;这些蛋白参与信号转导、蛋白质折叠和降解以及形态进化该基因编码90 kDa热休克蛋白的组成形式,被认为在胃细胞凋亡和炎症中起作用。选择性剪接导致多个转录变体假基因已经在多条染色体上被鉴定出来。[由RefSeq提供,2012年12月]This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Dec 2012]
HSP90AB1突变与药物: