基因名称：HSPA8 （heat shock protein family A (Hsp70) member 8）
别名： LAP1,HSC54,HSC70,HSC71,HSP71,HSP73,LAP-1,NIP71,HEL-33,HSPA10,HEL-S-72p
基因ID：3312
Chromosome(GRCh37) ：11 Start: 122928200 End: 122933074 Strand:
信号通路：
靶向药：
化疗药：
简介：这个基因编码热休克蛋白70家族的一个成员，它包含热诱导和组成性表达的成员。这种蛋白质属于后者，也被称为热休克同源蛋白它作为一种伴侣，与新生的多肽结合以促进正确的折叠。它还作为一种atp酶，在膜组分通过细胞运输过程中分解氯氰菊酯包被的囊泡另外，已经发现该基因编码不同亚型的剪接转录变体[由RefSeq提供，2011年8月]This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
HSPA8突变与药物：
