基因名称：IFNGR1 （interferon gamma receptor 1）
别名： CD119,IFNGR,IMD27A,IMD27B
基因ID：3459
Chromosome(GRCh37) ：6 Start: 137518621 End: 137540981 Strand:
信号通路：
靶向药：
化疗药：
简介：这个基因（ifngr1）编码γ干扰素受体的配体结合链（α）。人干扰素γ受体是ifngr1和ifngr2的异二聚体。ifngr1基因变异与幽门螺杆菌感染易感性有关。此外，ifngr1的缺陷是孟德尔对分枝杆菌病（也称为家族性播散性非典型分枝杆菌感染）易感性的原因。[由RefSeq提供，2008年7月]This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]
IFNGR1突变与药物：
