基因名称:KIF23 (kinesin family member 23)
别名: CHO1,KNSL5,MKLP-1,MKLP1
基因ID:9493
Chromosome(GRCh37) :15 Start: 69706585 End: 69740764 Strand: 1
信号通路:
靶向药:
化疗药:
简介:该基因编码的蛋白质是运动蛋白样蛋白家族的一员。这个家族包括在细胞分裂过程中运输细胞器和移动染色体的微管依赖性分子马达。这种蛋白已被证明能跨接反平行微管并在体外驱动微管运动。这种基因的交替剪接导致多个转录变体。The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants.
KIF23突变与药物:
EXPRESSION
药物:
Ziv-阿柏西普
疾病:
肝细胞癌