基因名称:KMT2E (lysine methyltransferase 2E)
别名: MLL5,NKp44L,ODLURO,HDCMC04P
基因ID:55904
Chromosome(GRCh37) :7 Start: 104654637 End: 104754532 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因是髓系/淋巴系或混合系白血病(MLL)家族的一员,编码一种带有N末端PHD锌指和中心集域的蛋白质过表达的蛋白质抑制细胞周期的进展。交替转录剪接变体已经被描述[由RefSeq提供,2008年7月]This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
KMT2E突变与药物: