基因名称:KMT5A (lysine methyltransferase 5A)
别名: SET8,SET07,SETD8,PR-Set7,PR/SET07
基因ID:387893
Chromosome(GRCh37) :12 Start: 123868704 End: 123893900 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码的蛋白是一种赖氨酸N-甲基转移酶,它能将组蛋白H4的Lys-20单甲基化以影响某些基因的转录抑制编码蛋白是细胞增殖所必需的,在染色质凝聚中起作用。[由RefSeq提供,2016年5月]The protein encoded by this gene is a protein-lysine N-methyltransferase that can monomethylate Lys-20 of histone H4 to effect transcriptional repression of some genes. The encoded protein is required for cell proliferation and plays a role in chromatin condensation. [provided by RefSeq, May 2016]
KMT5A突变与药物: