基因名称:LAG3 (lymphocyte activating 3)
别名: CD223
基因ID:3902
Chromosome(GRCh37) :12 Start: 6881678 End: 6887621 Strand: 1
信号通路:
靶向药:
化疗药:
简介:淋巴细胞活化蛋白3属于免疫球蛋白超家族,包含4个胞外免疫球蛋白样结构域。lag3基因包含8个外显子。序列数据、外显子/内含子组织和染色体定位均表明LAG3与CD4有密切关系。Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
LAG3突变与药物:
EXPRESSION
药物:
Ziv-阿柏西普
疾病:
雌激素受体阴性乳腺癌