MAGEH1靶向药基因

基因名称:MAGEH1  (MAGE family member H1)

别名: APR-1,APR1,MAGEH
基因ID:28986
Chromosome(GRCh37) :X Start: 55478538 End: 55479998 Strand: 1
信号通路:
靶向药:
化疗药:吉西他滨

简介:该基因属于黑色素瘤相关抗原(MAGE)超家族的非CT(非癌症/睾丸)亚群。编码蛋白可能与细胞凋亡、细胞周期停滞、生长抑制或细胞分化有关。该蛋白可能通过STAT1α(信号转导子和转录激活子1α)途径参与ATRA(全反式维甲酸)信号传导。This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily. The encoded protein is likely associated with apoptosis, cell cycle arrest, growth inhibition or cell differentiation. The protein may be involved in the atRA (all-trans retinoic acid) signaling through the STAT1-alpha (signal transducer and activator of transcription 1-alpha) pathway.
MAGEH1突变与药物:
EXPRESSION
药物:
吉西他滨 疾病:
胆管腺癌

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