基因名称:MNAT1 (MNAT1 component of CDK activating kinase)
别名: MAT1,TFB3,CAP35,RNF66
基因ID:4331
Chromosome(GRCh37) :14 Start: 61201459 End: 61435398 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码的蛋白与细胞周期素H和CDK7一起形成CDK激活激酶(CAK)酶复合物该复合物激活多种细胞周期蛋白相关激酶,也可与tfiih结合,通过rna聚合酶ii激活转录。已经发现了两个编码不同亚型的转录变体。[由RefSeq提供,2011年9月]The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
MNAT1突变与药物: