MX1靶向药基因

1,031

基因名称:MX1  (MX dynamin like GTPase 1)

别名: MX,MxA,IFI78,IFI-78K
基因ID:4599
Chromosome(GRCh37) :21 Start: 42792520 End: 42831141 Strand:
信号通路:
靶向药:
化疗药:

简介:该基因编码一种鸟苷三磷酸(GTP)代谢蛋白,参与细胞抗病毒反应该编码蛋白由Ⅰ型和Ⅱ型干扰素诱导,对抗几种不同rna和dna病毒的复制过程。在21号染色体上有一个与此基因相邻的相关基因,在4号染色体上有多个假基因选择性剪接导致多个转录变体[由RefSeq提供,2013年9月]This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
MX1突变与药物:

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