NCK1靶向药基因

基因名称:NCK1  (NCK adaptor protein 1)

别名: NCK,nck-1,NCKalpha
基因ID:4690
Chromosome(GRCh37) :3 Start: 136581050 End: 136670446 Strand:
信号通路:
靶向药:
化疗药:

简介:该基因编码的蛋白是Src同源2和3(SH2和SH3)结构域的信号转导蛋白之一它位于细胞质中,是一种衔接蛋白,参与从受体酪氨酸激酶向下游信号受体如ras的信号转导。另外还发现了编码不同亚型的剪接转录变体。[由RefSeq提供,2010年6月]The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010]
NCK1突变与药物:

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