基因名称:NKX3-1 (NK3 homeobox 1)
别名: NKX3,BAPX2,NKX3A,NKX3.1
基因ID:4824
Chromosome(GRCh37) :8 Start: 23536206 End: 23540450 Strand:
信号通路:
靶向药:
化疗药:
简介:这个基因编码一个含有转录因子的同源盒。这种转录因子在前列腺组织中作为上皮细胞生长的负调节因子。该基因的异常表达与前列腺癌的进展有关。交替剪接导致该基因的多个转录变体。[由RefSeq提供,2012年1月]This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012]
NKX3-1突变与药物: