基因名称:PALLD (palladin, cytoskeletal associated protein)
别名: MYN,PNCA1,CGI151,SIH002,CGI-151
基因ID:23022
Chromosome(GRCh37) :4 Start: 169418215 End: 169849608 Strand:
信号通路:
靶向药:
化疗药:
简介:这个基因编码一种细胞骨架蛋白,这是组织肌动蛋白细胞骨架所必需的。这种蛋白质是含有肌动蛋白微丝的一种成分,它参与控制细胞的形状、粘附和收缩。该基因多态性与1型胰腺癌易感性相关,也与心肌梗死风险相关。选择性剪接导致多个转录变体。[由RefSeq提供,2009年10月]This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
PALLD突变与药物: