基因名称:PDCD4 (programmed cell death 4 (neoplastic transformation inhibitor))
别名: H731
基因ID:27250
Chromosome(GRCh37) :10 Start: 112631565 End: 112659764 Strand: 1
信号通路:
靶向药:
化疗药:紫杉醇
简介:该基因是一种肿瘤抑制因子,编码一种与真核细胞翻译起始因子4A1结合并通过阻止RNA结合抑制其功能的蛋白质。选择性剪接导致多个转录变体。This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
PDCD4突变与药物:
EXPRESSION
药物:
紫杉醇 疾病:
肺癌