基因名称：PIK3CG （phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma）
别名： PI3K,PIK3,PI3CG,PI3Kgamma,p110gamma,p120-PI3K
基因ID：5294
Chromosome(GRCh37) ：7 Start: 106505723 End: 106547592 Strand:
信号通路： 细胞增殖
免疫相关
炎症相关
凋亡抑制
能量代谢
靶向药：
化疗药：
简介：磷酸肌醇3激酶（pi3ks）是肌醇磷脂的磷酸化产物，参与免疫应答。该基因编码的蛋白质是PI3K的I类催化亚单位，与其他I类催化亚单位（p110αp110β和p110δ）一样，编码蛋白结合p85调节亚单位形成pi3k，该基因位于先前在髓性白血病中发现的第7号染色体的一个普遍缺失片段。已经发现了一些编码相同蛋白质的转录变体。[由RefSeq提供，2015年6月]Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015]
PIK3CG突变与药物：
