基因名称：PLPPR4 （phospholipid phosphatase related 4）
别名： LPR4,PHP1,PRG1,LPPR4,PRG-1
基因ID：9890
Chromosome(GRCh37) ：1 Start: 99729848 End: 99775140 Strand:
信号通路：
靶向药：
化疗药：
简介：该基因编码的蛋白属于脂磷酸磷酸酶（lpp）家族。lpps催化调节多种细胞功能的生物活性脂质介质的脱磷。这种蛋白质在神经元中特异表达它位于外生轴突的膜中，在轴突发育和再生萌发过程中对轴突的外生具有重要作用。此外，还发现了编码不同亚型的剪接转录变体。[由RefSeq提供，2009年10月]The protein encoded by this gene belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. This protein is specifically expressed in neurons. It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
PLPPR4突变与药物：
