基因名称:POLDIP2 (DNA polymerase delta interacting protein 2)
别名: p38,POLD4,PDIP38
基因ID:26073
Chromosome(GRCh37) :17 Start: 26673659 End: 26684603 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码一种与dna聚合酶delta p50亚单位以及增殖细胞核抗原相互作用的蛋白质。编码蛋白可能在复制叉绕过dna损伤的能力中起作用。选择性剪接导致多个转录变体[由RefSeq提供,2014年2月]This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit, as well as with proliferating cell nuclear antigen. The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
POLDIP2突变与药物: