基因名称：PPP2R2A （protein phosphatase 2 regulatory subunit Balpha）
别名： B55A,PR52A,PR55A,B55ALPHA,PR55alpha
基因ID：5520
Chromosome(GRCh37) ：8 Start: 26149007 End: 26230196 Strand:
信号通路：
靶向药：
化疗药：
简介：该基因产物属于磷酸酶2调节亚基b家族。蛋白磷酸酶2是四种主要的ser/thr磷酸酶之一，与细胞生长和分裂的负调控有关。它由一种常见的异聚核心酶组成，由一个催化亚基和一个恒定的调节亚基组成，与多种调节亚基相结合。b调节亚基可能调节底物的选择性和催化活性。该基因编码调节亚单位b55亚家族的α亚型。另外，已经描述了剪接转录变体。[由RefSeq提供，2010年4月]The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
PPP2R2A突变与药物：
