基因名称：PPP2R5B （protein phosphatase 2 regulatory subunit B’beta）
别名： B56B,PR61B,B56beta
基因ID：5526
Chromosome(GRCh37) ：11 Start: 64692143 End: 64701950 Strand:
信号通路：
靶向药：
化疗药：
简介：该基因产物属于磷酸酶2a调节亚基b家族。蛋白磷酸酶2a是四种主要的ser/thr磷酸酶之一，与细胞生长和分裂的负调控有关。它由一种常见的异聚核心酶组成，由一个催化亚基和一个恒定的调节亚基组成，与多种调节亚基相结合b调节亚基可能调节底物的选择性和催化活性。该基因编码调节亚单位B56亚家族的β亚型[由RefSeq提供，2008年7月]The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. [provided by RefSeq, Jul 2008]
PPP2R5B突变与药物：
