基因名称:PRKACB (protein kinase cAMP-activated catalytic subunit beta)
别名: PKACB,PKAC-beta
基因ID:5567
Chromosome(GRCh37) :1 Start: 84543745 End: 84704181 Strand:
信号通路:
靶向药:
化疗药:
简介:这个基因编码的蛋白质是丝氨酸/苏氨酸蛋白激酶家族的成员编码蛋白是环腺苷酸依赖性蛋白激酶的催化亚单位,通过环腺苷酸介导信号传导。camp信号传导对细胞增殖和分化等过程具有重要作用。已观察到编码不同亚型的多个选择性剪接转录变体。[由RefSeq提供,2014年7月]The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2014]
PRKACB突变与药物: