基因名称:PRKDC (protein kinase, DNA-activated, catalytic subunit)
别名: HYRC,p350,DNAPK,DNPK1,HYRC1,IMD26,XRCC7,DNAPKc,DNA-PKC,DNA-PKcs
基因ID:5591
Chromosome(GRCh37) :8 Start: 48685669 End: 48872743 Strand:
信号通路: 细胞周期
基因组不稳定
靶向药:
化疗药:
简介:该基因编码dna依赖性蛋白激酶(dna-pk)的催化亚单位。与ku70/ku80异二聚体蛋白共同参与dna双链断裂修复和重组。编码的蛋白质是PI3/PI4激酶家族的成员。[由RefSeq提供,2010年7月]This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
PRKDC突变与药物: