基因名称：RARA （retinoic acid receptor alpha）
别名： RAR,NR1B1
基因ID：5914
Chromosome(GRCh37) ：17 Start: 38465423 End: 38513895 Strand:
信号通路： 细胞增殖
靶向药：
化疗药：
简介：这个基因代表一个核维甲酸受体。编码蛋白视黄酸受体α以配体依赖的方式调节转录。该基因参与调控时钟基因的发育、分化、凋亡、颗粒变性和转录。这个位点和其他几个位点之间的易位与急性早幼粒细胞白血病有关。另外，已经发现了这个位点的剪接转录变体。[由RefSeq提供，2010年9月]This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]
RARA突变与药物：
