基因名称:RICTOR (RPTOR independent companion of MTOR complex 2)
别名: AVO3,PIA,hAVO3
基因ID:253260
Chromosome(GRCh37) :5 Start: 38938021 End: 39074510 Strand: -1
信号通路: 细胞增殖
靶向药: AZD2014 AZD8055
CC-223
INK128 Sapanisertib
化疗药:
简介:Rictor和Mtor(frap1;mim 601231)是一种蛋白质复合物的组成部分,该复合物整合了营养和生长因子衍生的信号来调节细胞生长(Sarbassov等人,2004[PubMed 15268862])。RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).
RICTOR突变与药物:
AMPLIFICATION
药物:
AZD2014 AZD8055
CC-223
INK128 Sapanisertib
疾病:
胃腺癌 肺腺癌 小细胞肺癌