ROBO2靶向药基因

基因名称:ROBO2  (roundabout guidance receptor 2)

别名: SAX3
基因ID:6092
Chromosome(GRCh37) :3 Start: 75955845 End: 77699115 Strand:
信号通路:
靶向药:
化疗药:

简介:这个基因编码的蛋白质属于ROBO家族,是从苍蝇到人类高度保守的免疫球蛋白超家族的一部分编码蛋白是slit同源蛋白2的跨膜受体,在轴突引导和细胞迁移中发挥作用该基因突变与膀胱输尿管反流有关,其特征是尿液从膀胱回流到输尿管或肾脏。选择性剪接导致多个转录变体[由RefSeq提供,2014年2月]The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
ROBO2突变与药物:

常见问题
  • 如何在体龙基因完成所需的检测项目 流程简述 :在线咨询 - 采样送检 - 付款检测 - 检测分析 - 报告结果
查看详情

相关内容

官方客服团队

为您解决烦忧 - 24小时在线 专业服务