基因名称:RRAGC (Ras related GTP binding C)
别名: GTR2,RAGC,TIB929
基因ID:64121
Chromosome(GRCh37) :1 Start: 39303869 End: 39325495 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码GTR/RAG-GTP结合蛋白家族的一个成员编码蛋白是一种单体鸟嘌呤核苷酸结合蛋白,与rraga和rragb形成异二聚体,主要定位于细胞质。编码蛋白促进mTOR复合物的细胞内定位选择性剪接导致多个转录变体[由RefSeq提供,2012年12月]This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
RRAGC突变与药物: