基因名称：SCG5 （secretogranin V）
别名： 7B2,SgV,P7B2,SGNE1
基因ID：6447
Chromosome(GRCh37) ：15 Start: 32933757 End: 32989299 Strand:
信号通路：
靶向药：
化疗药：
简介：该基因编码一种分泌的伴侣蛋白，可防止其他分泌蛋白的聚集，包括与神经退行性疾病和代谢性疾病相关的蛋白该编码蛋白最为人所知的可能是其在前激素转化酶PC2（由基因ID:5126编码）的运输和激活中的作用已证明编码蛋白的磷酸化对其伴侣功能有抑制作用。该基因还产生一个ARHGAP11A-SCG5阅读转录物和ARHGAP11A-SCG5蛋白[由RefSeq提供，2019年2月]This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2 (encoded by Gene ID: 5126). Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb 2019]
SCG5突变与药物：
