基因名称:SF3A1 (splicing factor 3a subunit 1)
别名: PRP21,PRPF21,SAP114,SF3A120
基因ID:10291
Chromosome(GRCh37) :22 Start: 30727977 End: 30752931 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码剪接因子3a蛋白复合物的一个亚单位剪接因子3A异三聚体是成熟的U2小核核糖核蛋白颗粒(SNRNP)的组成部分。u2小核核糖核蛋白在剪接体组装和前mrna剪接中起关键作用。[由RefSeq提供,2014年8月]This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing. [provided by RefSeq, Aug 2014]
SF3A1突变与药物: