基因名称:SLC22A16 (solute carrier family 22 member 16)
别名: CT2,OAT6,OCT6,OKB1,FLIPT2,HEL-S-18,dJ261K5.1
基因ID:85413
Chromosome(GRCh37) :6 Start: 110745890 End: 110797844 Strand:
信号通路: 能量代谢
靶向药:
化疗药:
简介:该基因编码一个转运肉碱的两性离子转运蛋白家族成员。编码的蛋白质也被证明可以运输抗癌药物如博莱霉素(pmid:20037140),成功的治疗与肿瘤细胞中这种转运蛋白的活性水平有关。[由RefSeq提供,2011年12月]This gene encodes a member of the organic zwitterion transporter protein family which transports carnitine. The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells. [provided by RefSeq, Dec 2011]
SLC22A16突变与药物: