基因名称：SLC22A4 （solute carrier family 22 member 4）
别名： OCTN1,DFNB60
基因ID：6583
Chromosome(GRCh37) ：5 Start: 131630145 End: 131679899 Strand:
信号通路：
靶向药：
化疗药：
简介：在肝脏、肾脏、肠道和其他器官中的多特异性有机阳离子转运蛋白对于消除许多内源性小有机阳离子以及广泛的药物和环境毒素是至关重要的。编码蛋白是一种有机阳离子转运体和质膜完整蛋白，包含11个假定的跨膜结构域和核苷酸结合位点基序这种蛋白质的转运至少部分依赖于ATP[由RefSeq提供，2008年7月]Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent. [provided by RefSeq, Jul 2008]
SLC22A4突变与药物：
