SMARCC1靶向药基因

基因名称:SMARCC1  (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1)

别名: Rsc8,SRG3,SWI3,BAF155,CRACC1
基因ID:6599
Chromosome(GRCh37) :3 Start: 47627378 End: 47823405 Strand:
信号通路:
靶向药:
化疗药:

简介:这个基因编码的蛋白质是SWI/SNF蛋白家族的一员,其成员具有螺旋酶和ATPase活性,被认为通过改变这些基因周围的染色质结构来调节某些基因的转录编码蛋白是大的ATP依赖性染色质重塑复合物SNF/SWI的一部分,包含一个预测的亮氨酸拉链基序,这是许多转录因子的典型特征[由RefSeq提供,2008年7月]The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. [provided by RefSeq, Jul 2008]
SMARCC1突变与药物:

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