基因名称：SPINK1 （serine peptidase inhibitor, Kazal type 1）
别名： TCP,PCTT,PSTI,TATI,Spink3
基因ID：6690
Chromosome(GRCh37) ：5 Start: 147204143 End: 147218794 Strand:
信号通路： 细胞增殖
遗传相关
靶向药：
化疗药：
简介：该基因编码的蛋白质是胰蛋白酶抑制剂，由胰腺腺泡细胞分泌到胰液中。它被认为在防止胰蛋白酶催化的胰腺和胰管内酶原的过早激活方面起作用。该基因突变与遗传性胰腺炎和热带钙化性胰腺炎有关。[由RefSeq提供，2008年10月]The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]
SPINK1突变与药物：
