基因名称:SRGAP1 (SLIT-ROBO Rho GTPase activating protein 1)
别名: NMTC2,ARHGAP13
基因ID:57522
Chromosome(GRCh37) :12 Start: 64238276 End: 64541643 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码的蛋白质是一种GTPase激活剂,与GTPase CDC42协同作用,负性调节神经元的迁移编码蛋白与跨膜受体ROBO1相互作用,使CDC42失活[由RefSeq提供,2016年9月]The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42. [provided by RefSeq, Sep 2016]
SRGAP1突变与药物: