基因名称:STAG1 (stromal antigen 1)
别名: SA1,MRD47,SCC3A
基因ID:10274
Chromosome(GRCh37) :3 Start: 136055077 End: 136471245 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因是scc3家族的一员,在细胞核中表达。它编码一种多亚单位蛋白质复合物-黏着素的成分,这种复合物通过前期和前期的DNA复制,沿着染色体长度提供姐妹染色单体的黏着,然后在后期分离。[由RefSeq提供,2008年7月]This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase. [provided by RefSeq, Jul 2008]
STAG1突变与药物: