基因名称：STMN1 （stathmin 1）
别名： C1orf215,LAP18,Lag,OP18,PP17,PP19,PR22,SMN
基因ID：3925
Chromosome(GRCh37) ：1 Start: 26210672 End: 26233482 Strand: -1
信号通路：
靶向药：
化疗药：紫杉醇
简介：该基因属于Stathmin基因家族。它编码一种普遍存在的细胞溶质磷蛋白，作为整合细胞环境调节信号的细胞内继电器发挥作用。编码蛋白通过破坏微管的稳定性参与微管丝系统的调节。它可以防止装配和促进微管的拆卸。已发现编码该基因不同亚型的多种转录变体。This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
STMN1突变与药物：
EXPRESSION
药物：
紫杉醇 疾病：
子宫内膜癌
