TBL3靶向药基因

基因名称:TBL3  (transducin beta like 3)

别名: SAZD,UTP13
基因ID:10607
Chromosome(GRCh37) :16 Start: 2022064 End: 2028751 Strand:
信号通路:
靶向药:
化疗药:

简介:由该基因编码的蛋白质与含有wd40重复序列的蛋白质家族成员具有序列相似性。WD40是一个蛋白质大家族,似乎具有调节功能wd40重复序列介导蛋白质与蛋白质的相互作用,其家族成员参与信号转导、rna处理、基因调控、囊泡转运、细胞骨架组装等过程,可能在细胞类型分化的调控中发挥作用。该基因有多个聚腺苷酸化位点。它可能有多个选择性剪接的转录变体,但这些变体尚未完全描述。[由RefSeq提供,2008年7月]The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet. [provided by RefSeq, Jul 2008]
TBL3突变与药物:

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