TFG靶向药基因

基因名称:TFG  (trafficking from ER to golgi regulator)

别名: TF6,HMSNP,SPG57,TRKT3
基因ID:10342
Chromosome(GRCh37) :3 Start: 100428128 End: 100467811 Strand:
信号通路:
靶向药:
化疗药:

简介:有文献记载有几种融合癌蛋白部分由该基因编码。该基因还参与了导致间变性淋巴瘤和混合型软骨肉瘤的几种癌基因重排,并可能在NF-kappaB途径中发挥作用已发现该基因的多个转录变体。[由RefSeq提供,2010年9月]There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
TFG突变与药物:

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