基因名称:TLX3 (T cell leukemia homeobox 3)
别名: RNX,HOX11L2
基因ID:30012
Chromosome(GRCh37) :5 Start: 170736288 End: 170739138 Strand:
信号通路:
靶向药:
化疗药:
简介:这个基因编码的蛋白质是一个孤儿同源框蛋白,编码一个dna结合的核转录因子。涉及该基因的易位[t(5;14)(q35;q32)]与儿童和青年t细胞急性淋巴细胞白血病(t-all)有关。[由RefSeq提供,2015年11月]The protein encoded by this gene is an orphan homeobox protein that encodes a DNA-binding nuclear transcription factor. A translocation [t(5;14)(q35;q32)] involving this gene is associated with T-cell acute lymphoblastic leukemia (T-ALL) in children and young adults. [provided by RefSeq, Nov 2015]
TLX3突变与药物: