TNFRSF17靶向药基因

基因名称:TNFRSF17  (TNF receptor superfamily member 17)

别名: BCM,BCMA,CD269,TNFRSF13A
基因ID:608
Chromosome(GRCh37) :16 Start: 12058964 End: 12061925 Strand:
信号通路:
靶向药:
化疗药:

简介:这个基因编码的蛋白质是肿瘤坏死因子受体超家族的一员。该受体在成熟的b淋巴细胞中优先表达,可能对b细胞的发育和自身免疫反应具有重要意义。该受体与肿瘤坏死因子(配体)超家族成员13b(TNFSF13B/TALL-1/BAFF)特异性结合,导致NF-kappaB和MAPK8/JNK活化这种受体还与traf家族的不同成员结合,因此可以传递细胞生存和增殖的信号。[由RefSeq提供,2008年7月]The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
TNFRSF17突变与药物:

常见问题
  • 如何在体龙基因完成所需的检测项目 流程简述 :在线咨询 - 采样送检 - 付款检测 - 检测分析 - 报告结果
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