基因名称:TRIO (trio Rho guanine nucleotide exchange factor)
别名: tgat,MEBAS,MRD44,ARHGEF23
基因ID:7204
Chromosome(GRCh37) :5 Start: 14143817 End: 14510313 Strand:
信号通路:
靶向药:
化疗药:
简介:这个基因编码一个大蛋白,作为一个gdp到gtp的交换因子。这种蛋白质促进肌动蛋白细胞骨架的重组,从而在细胞迁移和生长中发挥作用。选择性剪接导致多个转录变体[由RefSeq提供,2015年12月]This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
TRIO突变与药物: