基因名称：TRPC5 （transient receptor potential cation channel subfamily C member 5）
别名： TRP5,PPP1R159
基因ID：7224
Chromosome(GRCh37) ：X Start: 111017542 End: 111326004 Strand:
信号通路：
靶向药：
化疗药：
简介：该基因属于瞬时受体家族。它编码七种哺乳动物TRPC（瞬时受体电位通道）蛋白之一编码蛋白是一种多道膜蛋白，被认为是一种受体激活的非选择性钙离子通道该蛋白单独或与trpc1、trpc3和trpc4作为异多聚体组装而具有活性。它还与多种蛋白质相互作用，包括钙调素、CABP1、enkurin、Na+-H+交换调节因子（NHERF）、干扰素诱导的GTP结合蛋白（MX1）、无名指蛋白24（RNF24）和含有SEC14结构域和谱蛋白重复序列的蛋白1（SESTD1）[由RefSeq提供，2010年5月]This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). [provided by RefSeq, May 2010]
TRPC5突变与药物：
