基因名称:VEGFC (vascular endothelial growth factor C)
别名: VRP,Flt4-L,LMPH1D,LMPHM4
基因ID:7424
Chromosome(GRCh37) :4 Start: 177604689 End: 177713899 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码的蛋白是血小板衍生生长因子/血管内皮生长因子(pdgf/vegf)家族的成员。编码蛋白促进血管生成和内皮细胞生长,并能影响血管的通透性。前蛋白进一步被切割成一个完全加工的形式,可以结合和激活vegfr-2和vegfr-3受体。[由RefSeq提供,2014年4月]The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014]
VEGFC突变与药物: