来源:医学之声近日,世界卫生组织(WHO)国际癌症研究机构公布了最新的致癌物清单,随后中国食品药品监督管理总局(CFDA)也发布了此官方版的“致癌物”完整清单,为大家提供指导和对照。此次致癌物清单总共4类:第一类致癌物,有「明确」的致癌作用,116种第二类致癌物,有「可能」的致癌作用 ,357种第三类致癌物,有「证据不明确」致癌作用,499种第四类致癌物,有「不太可能」的致癌作用,(1种)第一类致癌物清单一类致癌物指导致人类癌症的证据很明确,也就是说这些物质真的会致癌!序号英文名称中文名称确定时间(年)1Acetaldehyde associated with consumption of alcoholic beverages随酒精饮料摄入的乙醛20122Acheson process, occupational exposure associated with艾其逊法(用焦炭和粘土混合加热制造石墨的工业方法),职业暴露相关20173Acid mists, strong inorganic强无机酸雾20124Aflatoxins黄曲霉毒素20125Alcoholic beverages酒精饮料20126Aluminium production铝产品201274-Aminobiphenyl4-氨基联苯20128Areca nut槟榔果20129Aristolochic acid马兜铃酸201210Aristolochic acid, plants containing包含马兜铃酸的植物201211Arsenic and inorganic arsenic compounds砷和无机砷化合物201212Asbestos (all forms, including actinolite, amosite, anthophyllite, chrysotile, crocidolite, tremolite)铁石棉,石棉(各种形式,包括阳起石直闪石,温石棉,青石棉、透闪石)201213Auramine production金胺产品201214Azathioprine硫唑嘌呤201215Benzene苯201216Benzidine对二氨基联苯201217Benzidine, dyes metabolized to联苯胺、染料代谢201218Benzo[ a ]pyrene苯并芘(出现在熏烤、高温油炸食品中)201219Beryllium and beryllium compounds铍和铍化合物201220Betel quid with tobacco含烟草的槟榔嚼块201221Betel quid without tobacco不含烟草的槟榔嚼块201222Bis(chloromethyl)ether; chloromethyl methyl ether (technical-grade)二氯甲基醚;一氯甲基醚(技术等级)201223Busulfan白消安2012241,3-Butadiene1,3-丁二烯201225Cadmium and cadmium compounds镉及镉化合物201226Chlorambucil苯丁酸氮芥201227Chlornaphazine萘氮芥201228Chromium (VI) compounds铬(VI)化合物201229Ciclosporin环孢素201230Clonorchis sinensis (infection with)华支睾吸虫(感染)201231Coal gasification煤的气化201232Coal, indoor emissions from household combustion of家庭燃烧的煤,室内排放201233Coal-tar distillation煤焦油蒸馏201234Coal-tar pitch煤焦油沥青201235Coke production焦炭产品201236Cyclophosphamide环磷酰胺201237Cyclosporine环孢霉素2012381,2-Dichloropropane1,2-二氯丙烷201639Diethylstilbestrol己烯雌酚201240Engine exhaust, diesel发动机排放、柴油201341Epstein-Barr virus巴尔病毒201242Erionite毛沸石201243Estrogen therapy, postmenopausal雌激素治疗绝经后201244Estrogen-progestogen menopausal therapy (combined)雌激素-孕激素更年期治疗(联合)201245Estrogen-progestogen oral contraceptives (combined)雌激素-孕激素口服避孕药(组合)201246Ethanol in alcoholic beverages酒精饮料中的乙醇201247Ethylene oxide环氧乙烷201248Etoposide依托泊苷201249Etoposide in combination with cisplatin and bleomycin依托泊苷结合顺铂和博来霉素201250Fission products, including strontium-90裂变产物,包括锶- 90201251Fluoro-edenite fibrous amphibole氟代-浅闪石纤维角闪石201752Formaldehyde甲醛,福尔马林201253Haematite mining (underground)赤铁矿矿业(地下)201254Helicobacter pylori (infection with)幽门螺杆菌(感染)201255Hepatitis B virus (chronic infection with)乙型肝炎病毒(慢性感染)201256Hepatitis C virus (chronic infection with)丙型肝炎病毒(慢性感染)201257Human immunodeficiency virus type 1 (infection with)人类免疫缺陷病毒I型(感染)201258Human papillomavirus types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59人类乳头瘤病毒类型16,18,31,33,35,39,45,51,52,56,58,59201259Human T-cell lymphotropic virus type I人类T淋巴细胞病毒I型201260Ionizing radiation (all types)电离辐射(所有类型)201261Iron and steel founding (occupational exposure during)钢铁铸造(职业暴露)201262Isopropyl alcohol manufacture using strong acids使用强酸生产异丙醇201263Kaposi sarcoma herpesvirus卡波济肉瘤疱疹病毒201264Leather dust皮革尘埃201265Magenta production品红染料产品201266Melphalan美法仑201267Methoxsalen (8-methoxypsoralen) plus ultraviolet A radiation甲氧沙林2012甲氧补骨脂素花椒毒素紫外线辐射68Methyl-CCNU甲基环已亚硝脲2012694,4′-Methylenebis(2-chloroaniline) (MOCA)4,4′-亚甲基(2-氯苯胺)201270Mineral oils, untreated or mildly treated矿物油,未经处理或温和治疗201271MOPP and other combined chemotherapy including alkylating agentsMOPP(氮芥、长春新碱、甲基苄肼、强的松)和其他联合化疗包括烷化剂2012722-Naphthylamine2-萘胺201273Neutron radiation中子辐射201274Nickel compounds镍化合物201275N’-Nitrosonornicotine (NNN) and 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK)亚硝基降烟碱,亚硝胺201276Opisthorchis viverrini(infection with)泰国肝吸虫(麝猫后睾吸虫、香猫肝吸虫)(感染)201277Outdoor air pollution室外空气污染201678Outdoor air pollution, particulate matter in室外空气污染,颗粒物201679Painter (occupational exposure as a)画家(职业暴露)2012803,4,5,3’,4’-Pentachlorobiphenyl (PCB-126)多氯联苯2012812,3,4,7,8-Pentachlorodibenzofuran多氯二苯并呋喃201282Phenacetin非那西汀201283Phenacetin, analgesic mixtures containing非那西汀,包含止痛剂混合物201284Phosphorus-32, as phosphate磷-32,磷酸201285Plutonium钚201286Polychlorinated biphenyls多氯联苯201687Polychlorinated biphenyls, dioxin-like, with a Toxicity Equivalency Factor (TEF) according to WHO (PCBs 77, 81, 105, 114, 118, 123, 126, 156, 157, 167, 169, 189)类二恶英多氯联苯,毒性等价系数(TEF)取自WHO(多氯联苯77,77,81,77,81,123,126,156,157,167,169,189)201688Radioiodines, including iodine-131放射性碘,包括碘- 131201289Radionuclides, alpha-particle-emitting, internally deposited放射性核素,α粒子放射,内部沉积201290Radionuclides, beta-particle-emitting, internally deposited放射性核素,β粒子放射,内部沉积201291Radium-224 and its decay products镭- 224及其衰变产物201292Radium-226 and its decay products镭- 226及其衰变产物201293Radium-228 and its decay products镭- 228及其衰变产物201294Radon-222 and its decay products氡- 222及其衰变产物201295Rubber manufacturing industry橡胶制造业201296Salted fish, Chinese-style中国式咸鱼201297Semustine [1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea, Methyl-CCNU]司莫司丁(甲基环己亚硝脲)201298Shale oils页岩油201299Silica dust, crystalline, in the form of quartz or cristobalite二氧化硅粉尘、水晶、石英、方石英的形式2012100Solar radiation太阳辐射2012101Soot (as found in occupational exposure of chimney sweeps)烟尘(发现于烟囱清洁工的职业暴露)2012102Sulfur mustard硫芥2012103Tamoxifen他莫昔芬20121042,3,7,8-Tetrachlorodibenzo-para-dioxin四氯双苯环二噁英(TCDD)2012105Thiotepa三胺硫磷2012106Thorium-232 and its decay products钍- 232及其衰变产物2012107Tobacco smoke, second-hand吸二手烟2012108Tobacco smoking吸烟2012109Tobacco, smokeless无烟烟草(鼻烟、唇烟等)2012110ortho-Toluidine邻甲苯胺2012111Treosulfan苏消安2012曲奥舒凡112Trichloroethylene三氯乙烯2014113Ultraviolet-emitting tanning devices紫外线放射日光浴设备2012114Vinyl chloride氯乙烯2012115Wood dust木屑2012116X- and Gamma-RadiationX、伽马辐射2012除了最近讨论很多的马兜铃酸是一类致癌物之外,常吃的咸鱼也是一类致癌物。咸鱼作为“重口味”食物代表,是广受大家欢迎的下饭菜。但是你不知道的是,咸鱼等重口味食物在制作时需要经过高浓度的盐长时间腌制,而且中式咸鱼有脱水的步骤。这一加工方式和过程会产生大量的二甲基亚硝酸盐,这种物质进入人体后,会转化成致癌性很强的二甲基亚硝胺。吃多了,会导致胃、肠、胰腺等消化道癌变几率升高。所以,以后要尽量少吃咸鱼、咸菜等腌制食物,避免“癌从口入”。二类致癌物二类致癌物是指导致人类癌症的证据不明确的物质,简单说就是,有致癌的可能性但是也不一定致癌!确定时间成分主要来源1987丙烯酰胺 薯条、薯片、油条等高温处理的食物1987黄樟素发霉的生姜1993黄曲霉毒素M1常见于饲料被霉菌污染的牛所产的牛奶19934-甲基咪唑常见于酱油、可乐2013沥青暴露于氧化沥青及其在屋顶过程中的排放2006铅含铅汽油造成的城市铅污染2014少量芳烃族化合物汽油三类致癌物品导致动物和人致癌的证据都不明确,其实这一类导致癌症的可能性非常小。苏丹红、印刷油墨、次氯酸盐、汞及汞有机化合物、聚丙烯、聚乙烯、聚氯乙烯、玻璃纤维、茶叶、茶碱、糖精、静态磁场、维生素K、胆固醇、灭草隆等。提示不要以为只要是一类致癌物就都厉害,致癌物的分级只是看致癌证据是否充分,而不是看它导致癌症的能力强不强。
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