WWP1靶向药基因

基因名称:WWP1  (WW domain containing E3 ubiquitin protein ligase 1)

别名: AIP5,Tiul1,hSDRP1
基因ID:11059
Chromosome(GRCh37) :8 Start: 87354965 End: 87480181 Strand:
信号通路:
靶向药:
化疗药:

简介:ww结构域蛋白广泛存在于真核生物中,在蛋白质降解、转录和rna剪接等多种细胞功能的调控中发挥着重要作用。该基因编码一个包含4个串联WW结构域和一个HECT(与E6相关蛋白羧基末端同源)结构域的蛋白质。编码的蛋白质属于NEDD4样蛋白家族,它是E3泛素连接酶分子,调节关键的转运决定,包括将蛋白质靶向蛋白质体或溶酶体该基因的选择性剪接产生至少6个转录变体;然而,这些转录的全长性质尚未确定[由RefSeq提供,2008年7月]WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq, Jul 2008]
WWP1突变与药物:

常见问题
  • 如何在体龙基因完成所需的检测项目 流程简述 :在线咨询 - 采样送检 - 付款检测 - 检测分析 - 报告结果
查看详情

相关内容

官方客服团队

为您解决烦忧 - 24小时在线 专业服务