基因名称:XRCC2 (X-ray repair cross complementing 2)
别名: FANCU
基因ID:7516
Chromosome(GRCh37) :7 Start: 152343583 End: 152373250 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码reca/rad51相关蛋白家族的一个成员,参与同源重组以维持染色体稳定性和修复dna损伤。该基因通过同源重组参与dna双链断裂的修复,并在功能上与中国仓鼠irs1互补,irs1是一种修复缺陷突变体,对多种不同的dna损伤剂表现出超敏反应。[由RefSeq提供,2008年7月]This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq, Jul 2008]
XRCC2突变与药物: